Typically, methylation of nucleosome N-terminal tails leads to

Typically, methylation of nucleosome N-terminal tails leads to
a. relaxed packaging of the chromatin and increased transcription
b. activation of topoisomerase
c. removal of the protein components of the chromatin from the DNA
d. increased amounts of euchromatin relative to heterochromatin
e. tighter packaging of the chromatin and reduced transcription